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Chitosan oligosaccharides (COS) have attracted considerable attention in poultry research due to their diverse biological activities and possible effects on the welfare and productivity of broiler chickens. A thorough examination of many studies indicates that the influence of COS on indices such as antioxidative functions, growth performance, immunological responses, and metabolic implications in broilers is significant. For example, specific dosage levels of COS have significantly enhanced antioxidant activity, regulation of cholesterol levels, and improved growth performance. The research findings have provided evidence for COS's antioxidative and anti-inflammatory properties and its capacity to mitigate the effects caused by stress. Nevertheless, the effectiveness of reactions might be influenced by the dosage and may demonstrate variances. Broiler chickens are suggested to consume dietary COS levels between 350 mg/kg and 500 mg/kg feed to obtain antioxidant and immunological advantages. Nevertheless, the most favorable results regarding growth and the ability to absorb nutrients are typically found when the intake ranges from 0.5 g/kg to 1.0 g/kg feed. For yellow-feather broilers experiencing heat stress, it is advisable to administer a dosage of 200 mg/kg feed of COS. However, it is essential to closely observe dosages exceeding 2.5 g/kg since they may significantly impair growth performance. The diverse research on using COS in broiler management has provided valuable insights into its intricate nature. This review has highlighted the potential benefits of COS in enhancing chicken health and nutrition. However, it has also underscored the need for additional research to optimize its effectiveness in broiler production fully. It can be concluded that dietary COS in broiler chickens in doses ranging from 200 mg to 1000 mg/kg feed has a positive effect on growth performance, antioxidative properties, regulation of lipid metabolism, ability to mitigate stress, impact on meat quality, and carcass traits, but exceeding 2.5 g/kg feed may significantly impair in growth performance in the broiler.
Harahap et al. (Mon,) studied this question.