Background: Breast and thyroid cancers pose an increasing public-health burden. Ultrasound imaging is a cost-effective, real-time modality for lesion detection and segmentation, yet suffers from speckle noise, overlapping structures, and weak global-local feature interactions. Existing networks struggle to reconcile high-level semantics with low-level spatial details. We aim to develop a segmentation framework that bridges the semantic gap between global context and local detail in noisy ultrasound images. Methods: We propose UESA-Net, a U-shaped network with multidirectional shrinkage attention. The encoder-decoder architecture captures long-range dependencies and fine-grained structures of lesions. Within each encoding block, attention modules operate along horizontal, vertical, and depth directions to exploit spatial details, while a shrinkage (threshold) strategy integrates prior knowledge and local features. The decoder mirrors the encoder but applies a pairwise shrinkage mechanism, combining prior low-level physical cues with corresponding encoder features to enhance context modeling. Results: On two public datasets - TN3K (3493 images) and BUSI (780 images) - UESA-Net achieved state-of-the-art performance with intersection-over-union (IoU) scores of 0.8487 and 0.6495, respectively. Conclusions: UESA-Net effectively aggregates multidirectional spatial information and prior knowledge to improve robustness and accuracy in breast and thyroid ultrasound segmentation, demonstrating superior performance to existing methods on multiple benchmarks.
Shi et al. (Fri,) studied this question.