The mechanism of borohydride reductions. Part 2: 4-t-butyl-cyclohexanone – Dispersion induced stereochemistry.

Key Points

• Stereochemistry is affected by the dispersion processes during reduction.
• The study identifies changes in stereochemistry relevant to borohydride reductions.
• Analysis of stereochemistry in reduction involves both chemical and physical factors.
• Understanding the interaction of borohydride with tert-butyl-cyclohexanone may inform synthetic methods.