Abstract Objective To evaluate the effects of interactive cognitive-motor training on balance, mobility and cognition in people with chronic stroke. Design A systematic search of the Medline, EMBASE, Cochrane Library, and PsycINFO databases from inception to 11 June 2025 to identify relevant randomized controlled trials. Trials investigating the effects of cognitive-motor training interventions with balance, mobility, and cognition outcomes in chronic stroke survivors. Results Forty-four trials involving 1,422 people with chronic stroke were included. The meta-analyses revealed interactive cognitive-motor training significantly improved mobility (Timed Up and Go Test and Dynamic Gait Index), gait speed, and dynamic balance (Berg Balance Scale and Functional Reach Test), but not postural sway, lower limb motor function (Fugl-Meyer Assessment of Lower Extremity) or executive function (Trail Making Test-B). No subgroup differences were observed with respect to intervention type, dose, or duration. Conclusions Interactive cognitive-motor training represents a promising approach for improving balance, mobility, and gait speed in people with chronic stroke. However, the optimal intervention dose and long-term effects remain unclear. Standardized protocols, increased accessibility, and further research on home-based interventions are necessary to optimize clinical applications and improve long-term outcomes for stroke rehabilitation.
Lapanan et al. (Thu,) studied this question.
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