What question did this study set out to answer?

The aim is to develop a targeted therapy for effective copper chelation in Wilson's disease using a metal-organic framework.

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January 22, 2026Open Access

d -Penicillamine-loaded MIL-100(Fe) for precise targeted copper chelation in Wilson's disease

The aim is to develop a targeted therapy for effective copper chelation in Wilson's disease using a metal-organic framework.
Utilized MIL-100(Fe) as a delivery system for d-Penicillamine.
Focused on precise targeting mechanisms for copper chelation.
Evaluated the effectiveness in Wilson's disease treatment.
Achieved effective targeting of copper ions.
Demonstrated improved therapeutic outcomes in Wilson's disease models.
Showed enhanced stability and release profile of d-Penicillamine.

d -Penicillamine-loaded MIL-100(Fe) for precise targeting copper chelation in Wilson's disease.