Background & Objective: Cancer remains a global health challenge, with current therapies often limited. Ayurveda describes Rasaushadis as a potent mediicne effective even in small doses. Raudra Rasa is a a classical Ayurvedic formulation which is specifically mentioned under Arbuda Chikitsa in various Granthas. The present study was undertaken to evaluate Raudra Rasa1 with respect to its Pharmaceutical preparation, Analytical study, Safety and Anti-cancer potential. Methods: Raudra Rasa1 was prepared as per the classical reference. For this Kajjali2 was prepared by taking Samaguna of Shuddha Parada and Shuddha Gandhaka. This Kajjali2 was subjected to Bhavana with Swarasa of Nagavalli, Meghanada, Punarnava and Gomutra-Pippali Kashaya which was subjected to Laghuputa.3 After successfully obtaining the final product, it was sent for analytical and physio-chemical analysis. Results: The results showed that the prepared formulation was well tolerated at therapeutic dose and showed significant improvements in hematological parameters, reduction in tumor volume, and increased survival time in Acute toxicity study and animal experimental study in EAC4 model respectively. Interpretation & Conclusion: Considering all the reports it can be concluded that the study provides scientific evidence to support the classical claims of Raudra Rasa having potential to be prescribed in Arbuda condition.
Dr. Malavika V. S.1*, Dr. Malavi Shayan2, Dr. Vikram S.3 (Sun,) studied this question.