What question did this study set out to answer?

The research aims to assess the prognostic significance of PPFIA2 in localized prostate cancer.

February 2, 2026

Prognostic Significance of PPFIA2 in Localized Prostate Cancer: Integrative Analysis and Functional Validation.

Key Points

The research aims to assess the prognostic significance of PPFIA2 in localized prostate cancer.
Integrative analysis of PPFIA2 expression levels
Functional validation of its effects in prostate cancer cells
Evaluation of its role in risk stratification and therapy
PPFIA2 is identified as an unfavorable prognostic biomarker.
Its oncogenic effects suggest a potential in targeted therapy.
Risk stratification can be enhanced with PPFIA2 assessment.

Abstract

PPFIA2 is an unfavorable prognostic biomarker for localized PCa. Its oncogene effect highlights its potential for risk stratification and targeted therapy.

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Authors

Jipu Liu

Jinan University

Cheng Ya Hsu

First Affiliated Hospital of Guangzhou Medical University

Nagarajan Vaidehi

City Of Hope National Medical Center

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Institutions

University of California, Riverside

Jinan University

Guangzhou Medical University

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Prognostic Significance of PPFIA2 in Localized Prostate Cancer: Integrative Analysis and Functional Validation.

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Abstract

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Discussion

Authors

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