Abstract Background: Renal involvement is a common but often overlooked complication of rheumatological disorders, contributing to significant morbidity. Aim: This study aimed to determine the prevalence and spectrum of renal involvement in rheumatological diseases and identify associated clinical and laboratory features. Settings and Design: A hospital-based, cross-sectional observational study conducted at a tertiary care center in North India. Materials and Methods: Fifty consecutive adults with rheumatological disorders and renal manifestations were evaluated using clinical, laboratory, and immunological assessments, with renal biopsy where indicated. Results: Systemic lupus erythematosus was the most frequent underlying disease, with lupus nephritis predominating. Other patterns included drug-induced nephropathy and renovascular lesions. Autoimmune markers showed strong associations with specific renal pathologies. Conclusion: Renal involvement is frequent across rheumatological disorders, particularly in active disease. Routine screening and early recognition are essential to reduce renal morbidity.
Nasar et al. (Thu,) studied this question.
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