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February 9, 2026Open Access

Enteric neuroscience on the move: recording from the gut in vivo

MNMadeleine R. Di NataleThe University of Melbourne LSLincon A. StampThe University of Melbourne MHMarlene M. Hao

Key Points

The aim is to explore the electrophysiological activity of the enteric nervous system in vivo.
Developed a novel device for recording neuronal activity.
Conducted measurements in live, freely moving rodents.
Focused on the enteric nervous system.
Successfully recorded neuronal activity from the gut.
Demonstrated the feasibility of in vivo measurements.

Abstract

Investigating the electrophysiological activity of the enteric nervous system in vivo has been an immense challenge for researchers. In a recent study, Boys, Güemes et al. developed a novel device for recording neuronal activity from the gut in live, freely moving rodents.

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