Sarcopenia and recurrence risk in high-risk non–muscle-invasive bladder cancer: a nonlinear modeling approach

Key Points

• This research aims to explore how body composition affects recurrence risk in patients with high-risk non-muscle-invasive bladder cancer.
• Utilized nonlinear modeling techniques to assess body composition and recurrence risk.
• Analyzed associations between body and muscle mass and disease control outcomes.
• Evaluated existing definitions of sarcopenia for prognostic differences.
• Low and high body mass were linked to increased recurrence risk.
• Standardized multiparametric approaches improved prediction accuracy.
• Current sarcopenia definitions showed variability in prognostic value.