The study aims to explore how cells communicate with each other through gap junctions in biomimetic tissues.
Developed 2D biomimetic tissue models for investigation.
Utilized imaging techniques to observe cell interactions.
Analyzed the role of gap junctions in molecular exchange.
Demonstrated that gap junctions facilitate efficient communication between cells.
Found variations in cell communication based on tissue composition.
Observed that engineered models replicate native tissue behavior effectively.
Abstract
In tissues, cells in direct physical contact with each other can exchange ions or molecules via protein clusters called gap junctions, that form channels across the membranes of adjacent cells....