Preparation and MR Imaging Study of a Recombinant Surface Antibody Superparamagnetic Iron Oxide Nanoparticle–EPC1 Molecular Probe for Hepatic Alveolar Echinococcosis

Key Points

• The study aims to evaluate the efficacy of the SPION-EPC1 molecular probe in improving MRI detection of HAE lesions.
• Development of SPION-EPC1 molecular probe.
• Assessment of sensitivity and effectiveness in MRI imaging.
• Evaluation of long-lasting effects on detection.
• The SPION-EPC1 probe showed significantly improved sensitivity in detecting HAE lesions.
• Demonstrated long-lasting effects, enhancing MRI imaging capabilities.
• Promising potential for early diagnosis of hepatic alveolar echinococcosis.