Mechanism of action of MiR-330-5p targeting ITGA5 in the regulation of proliferation, migration, and invasionof gastric cancer

Key Points

• The study aims to explore how miR-330-5p influences gastric cancer cell behavior by targeting ITGA5.
• Examined the effects of miR-330-5p on gastric cancer cell lines.
• Investigated the interaction between miR-330-5p and ITGA5.
• Analyzed the involvement of the FAK/AKT signaling pathway in cellular responses.
• miR-330-5p significantly reduces proliferation of gastric cancer cells.
• Invasion and migration of gastric cancer cells decrease upon miR-330-5p overexpression.
• FAK/AKT signaling pathway is altered in response to the levels of miR-330-5p.