Transition-Metal-Free 4+2 Cyclocondensation of Diaryliodonium salts Accessing Phenazine, Phenothiazine, Phenoxazine and Dioxane Derivatives

Key Points

• The aim is to develop a transition-metal-free method to synthesize various heterocycles from diaryliodonium salts.
• Utilized ortho-fluorinated nitro-diaryliodonium salts as starting materials.
• Employed a transition-metal-free cyclocondensation approach.
• Demonstrated functional-group tolerance across different substrates.
• Successfully synthesized phenazine, phenothiazine, phenoxazine, and dioxane derivatives.
• Confirmed broad functional-group tolerance, allowing for various late-stage modifications.