This study was supported by the Swiss National Science Foundation (SNF grant no. 310030₁97408), the Swiss National Science Foundation via the National Center of Competence in Research (NCCR) TransCure, University of Bern, Switzerland (grant no. 51NF40₁85544) and the Swiss 3R Competence Centre (3RCC; grant no OC-2019-019). TF was supported by the Hans Sigrist Foundation, Switzerland.
Schroeder et al. (Fri,) studied this question.