Sutureless aortic valve replacement showed a non-significant higher early mortality rate (13.5%) compared to TAVI (5.7%) with comparable early clinical outcomes and distinct paravalvular leak profiles in high-risk severe aortic stenosis patients.
Observational (n=298)
No
Does sutureless aortic valve replacement improve early and 6-month clinical and hemodynamic outcomes compared to transcatheter aortic valve implantation in patients with severe aortic stenosis?
In high-risk patients with severe aortic stenosis, SU-AVR and TAVI offer complementary benefits, with TAVI providing shorter hospital stays and SU-AVR reducing the incidence of mild paravalvular leak.
Effect estimate: P = 0.173 for early mortality post-matching
Absolute Event Rate: 13.5% vs 5.7%
p-value: p=0.173
In selected high-risk patients, SU-AVR and TAVI showed complementary early profiles. Individualized Heart Team-based decision-making remains essential.
Bayici et al. (Mon,) conducted a observational in High-risk patients with severe aortic stenosis undergoing sutureless aortic valve replacement or transfemoral transcatheter aortic valve implantation (n=298). Sutureless aortic valve replacement (SU-AVR) vs. Transfemoral transcatheter aortic valve implantation (TAVI) was evaluated on Early (within 30 days) mortality and 6-month clinical and hemodynamic outcomes including paravalvular leak, transvalvular gradients, permanent pacemaker implantation, total hospital length of stay (P = 0.173 for early mortality post-matching, p=0.173). Sutureless aortic valve replacement showed a non-significant higher early mortality rate (13.5%) compared to TAVI (5.7%) with comparable early clinical outcomes and distinct paravalvular leak profiles in high-risk severe aortic stenosis patients.