Glutathione-activatable synthetic channel for hopping-mediated anion transport

Key Points

• The aim is to investigate a synthetic channel that can be activated by glutathione for effective anion transport.
• Synthesis of a glutathione-activatable anion channel.
• Comparison of ion channel activity before and after glutathione activation.
• Analysis of self-assembly properties of the synthetic channel.
• The doubly 2,4-dinitrobenzene-protected channel showed no ion activity initially.
• Activation with glutathione restored self-assembly and enabled significant ion transport.