Abstract PS5-04-29: Real-world treatment patterns and outcomes in hormone receptor positive Her2 negative early-stage breast cancer in a private community oncology practice of Brazil

Key Points

• Assess disease characteristics, treatment patterns, and outcomes for HR positive/HER2 negative early breast cancer in Brazil.
• Retrospective analysis from Oncoclínicas real-world database (2016-2021)
• Evaluated risk profiles: high-risk, intermediate-risk, low-risk
• Examined endocrine therapy and chemotherapy prescriptions
• Analyzed 3-year invasive disease-free survival rates
• 1,786 cases included, median age 57 years
• 66% of patients classified as low-risk, with significant use of aromatase inhibitors
• Suboptimal ovarian function suppression and chemotherapy rates in premenopausal high-risk patients
• 3-year invasive disease-free survival: 86% in low-risk, 87% in intermediate-risk, and 72% in high-risk groups