RCT: Omega‐3 fatty acids not supported as adjunct therapy for pediatric depression

Key Points

• To evaluate the effectiveness of omega-3 fatty acids as an adjunct therapy in children and adolescents with major depressive disorder.
• Conducted a randomized clinical trial (RCT) with a pediatric population.
• Administered omega-3 fatty acids (EPA and DHA) along with antidepressants.
• Compared the omega-3 treatment group to a placebo group.
• Omega-3 fatty acids did not show significant improvement over placebo in treating major depressive disorder.
• No substantial differences in depressive symptoms reported between the two groups.