An international collaborative initiative to screen primary ciliary dyskinesia with high-speed video microscopy and nasal nitric oxide at a tertiary referral centre in South India

Key Points

• To explore a combined screening strategy for primary ciliary dyskinesia (PCD) using high-speed video microscopy and nasal nitric oxide testing.
• International collaborative initiative conducted at a tertiary referral centre in South India.
• Used high-speed video microscopy and nasal nitric oxide testing as complementary screening methods.
• Conducted genetic testing in a subset of patients to confirm diagnosis.
• Found that the combined screening strategy helped identify likely PCD cases.
• Genetic testing confirmed diagnosis in 54% of tested patients.