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100 years of childhood acute lymphoblastic leukaemia in the UK | Synapse

February 25, 2026

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100 years of childhood acute lymphoblastic leukaemia in the UK

Key Points

To review the advancements in treatment and care for childhood acute lymphoblastic leukaemia over the last century in the UK.
Analysis of historical treatment data
Review of major UK Acute Lymphoblastic Leukaemia trials
Comparison of survival rates over the century
Significant improvements in survival rates observed
Increased effectiveness of treatment protocols developed through UK trials
Enhanced supportive care measures contributing to better patient outcomes

Abstract

This article summarises the developments and improvements in care over the past 100 years for paediatric patients with acute lymphoblastic leukaemia in the UK, highlighting the impressive contribution of the UK Acute Lymphoblastic Leukaemia trials to this.

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Cite This Study

Lane et al. (Mon,) studied this question.

synapsesocial.com/papers/699e91eaf5123be5ed04fc25 https://doi.org/https://doi.org/10.1136/archdischild-2025-330155