Effect of Hormone Replacement Therapy on Liver and Cardiometabolic Outcomes in Peri-Menopausal MASLD.

Key Points

• To investigate the effects of hormone replacement therapy on liver and cardiometabolic health in peri-menopausal individuals with MASLD.
• Evaluated the impact of hormone replacement therapy on individuals with pre-existing MASLD
• Followed patients over a 5-year period
• Compared liver and cardiometabolic outcomes between those receiving HRT and those not
• HRT is associated with a lower risk of major liver disease
• HRT is associated with a lower risk of cardiometabolic diseases
• Findings suggest benefits of HRT in managing peri-menopausal symptoms in relevant populations