Recent Advances in Decorating the meta-Position of Pyridines through Temporary Dearomatization Strategy

Key Points

• The study aims to explore site-selective C-H functionalization techniques for pyridines through dearomatization.
• Investigated the temporary dearomatization strategy on pyridine structures.
• Employed various C-H functionalization methods to achieve site-selectivity.
• Analyzed the effects of different substituents on pyridine reactivity.
• Demonstrated effective site-selective functionalization in pyridine derivatives.
• Outlined the potential for increased efficiency in medicinal and materials chemistry applications.