Prevalence of disorders of gut-brain-interaction in pediatric patients with in-remission inflammatory bowel disease: An Italian multicenter study.

Key Points

• This research aims to examine the prevalence of disorders of gut-brain interaction (DGBIs) in pediatric patients with inflammatory bowel disease (IBD) in remission.
• Conducted a multicenter observational study in pediatric patients with quiescent IBD and healthy controls.
• Compared the prevalence of DGBIs between IBD patients and control group.
• Analyzed psychological and nutritional factors as predictors of DGBIs.
• Found a numerically higher prevalence of DGBIs in IBD patients compared to controls, though not statistically significant.
• Identified significantly more upper gastrointestinal DGBIs in IBD patients.
• Determined that 5-ASA medication may lower the likelihood of developing DGBIs.