Association between hypothermic machine perfusion parameters and graft function in deceased donor kidney transplantation.

Key Points

• The research aims to explore how hypothermic machine perfusion parameters relate to graft function after kidney transplantation.
• Analyzed non-linear relationships between hypothermic machine perfusion parameters and delayed graft function.
• Developed a model for internal performance evaluation.
• Outlined need for external validation in independent cohorts.
• Identified complex interactions between HMP parameters and graft function.
• Demonstrated the model's effectiveness for early risk stratification post-transplant.
• Indicated a necessity for external validation to ensure findings are broadly applicable.