NODESINNDIANAD6. 3Report on in vivo studies | Synapse
February 27, 2026Open Access
NODESINNDIANAD6. 3Report on in vivo studies
Key Points
The study aims to evaluate the pharmacokinetics and biodistribution of an optimized apomorphine formulation.
Conducted in vivo studies using rat models
Administered the apomorphine loaded nanosponge formulation orally
Analyzed pharmacokinetic parameters and distribution in various tissues
Demonstrated effective absorption of the formulation after oral administration
Showed favorable biodistribution patterns in target tissues
Indicated potential for improved therapeutic effects compared to conventional formulations
Abstract
In vivo evaluation of the pharmacokinetics and biodistribution of the optimized apomorphine loaded nanosponge formulation after oral administration to rats.