What question did this study set out to answer?

To investigate the role of BDNF in hearing impairment and dendritic pruning in neonatal mice experiencing pain.

February 28, 2026Open Access

Correction: Reduced BDNF expression in the auditory cortex contributed to neonatal pain-induced hearing impairment and dendritic pruning deficiency in mice

Q: What does this research mean for the field?

Reduced BDNF expression in the auditory cortex contributes to neonatal pain-induced hearing impairment and dendritic pruning deficiency in mice. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

Key Points

To investigate the role of BDNF in hearing impairment and dendritic pruning in neonatal mice experiencing pain.
Analyzed BDNF expression in auditory cortex of neonatal mice
Assessed hearing capabilities through behavioral tests
Examined dendritic pruning patterns in neuronal cells
Reduced BDNF levels correlated with impaired hearing abilities
Dendritic pruning deficiency observed in affected mice
Neonatal pain exposure linked to these changes

Abstract

Li N, Chen B, Jia G, et al . Reduced BDNF expression in the auditory cortex contributed to neonatal pain-induced hearing impairment and dendritic pruning deficiency in mice. Reg Anesth Pain Med 2023;48:85-92. doi:10.1136/rapm-2022-103621 In the originally published article, figure 4 contained

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Correction: Reduced BDNF expression in the auditory cortex contributed to neonatal pain-induced hearing impairment and dendritic pruning deficiency in mice

Key Points

Abstract

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