A 28-year-old female presented with defective distance vision in both eyes for 1 year. Slit lamp evaluation revealed the presence of blue dot cataract (cerulean cataract) Figure 1a and b. It is an autosomal dominant condition caused by mutations in the βB2-crystallin (CRYBB2), CRYGD, and MAF genes. Beta crystallin gene maintains lens’ refractive index and transparency. Cerulean cataracts are developmental rather than congenital cataract, distinguished by their striking blue colour. Progression is slow, manifesting in the 3rd or 4th decade as gradual deterioration in distance vision. The striking bright blue colour of the opacities enhances the distinctiveness of the image.Figure 1: (a and b) Slit lamp photo depicting cerulean cataractAuthors statement The manuscript has been read and approved by all the authors. The requirements for authorship as stated earlier in this document have been met. Each author believes that the manuscript represents honest work. Ethical approval The study was evaluated by the Institutional Ethics Committee of Aravind Eye Hospital and deemed not to require ethics approval. Declaration of patient consent The authors certify that they have obtained all appropriate consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their image and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil financial interest. Conflict of interest The authors declare that there is no conflict of interest.
Tagare et al. (Thu,) studied this question.