Aim: This research compared and evaluated the setting time of four different biomaterials Mineral Trioxide Aggregate (MTA) Angelus, Biodentine, EndoSequence Root Repair Material (ERRM), and Bio-C Repair used for root-end filling in the presence of blood contamination. Methods: One hundred and sixty freshly extracted human teeth with single roots were selected for this research and root canal treatment was carried out on each tooth, followed by a root-end resection and preparation of a root-end cavity. The teeth were then randomly assigned to one of four groups, based on the biomaterial to be tested. The root end cavity was filled with biomaterial and the teeth were placed in an experimental setup with more than half of the roots submerged in blood. The setting time was estimated using the Vicat needle apparatus, which was used to measure and record the penetration depth of the needle at specific time intervals, starting from the initial setting time specified by the manufacturer for each material. Measurements were taken at 5-min intervals for each sample. The data collected were analyzed using a two-way analysis of variance. Results: The findings showed that MTA had the shortest setting time between 10 and 15 min when blood contamination was present, followed by ERRM 25–30 min. Bio-C Repair and Biodentine took notably longer to set which is more than 45 min and 27 min, respectively. Conclusion: It is essential to choose biomaterials with the shortest setting time when dealing with blood contamination.
Kesarwani et al. (Thu,) studied this question.