Innovating Patent Ductus Arteriosus Closure: Preclinical Evaluation of the First Iranian-Developed Nitinol Occluder in a Sheep Model.

Key Points

• Evaluate the safety and biocompatibility of an Iranian-developed nitinol occluder for PDA closure.
• Conducted preclinical tests in a sheep model
• Assessed feasibility and safety of the device
• Evaluated biocompatibility of materials used
• Demonstrated successful closure of PDA in the sheep model
• Showed good biocompatibility with surrounding tissues
• Indicated potential as a cost-effective alternative for PDA closure