Dynamics of interleukin-23/interleukin-17 axis and type 1 regulatory T cells across disease stages in axial spondyloarthritis

Key Points

• Investigate the role of interleukin-23 and regulatory T cells across different stages of axial spondyloarthritis.
• Analyzed immune activity related to IL-23 in axial spondyloarthritis
• Examined regulation of Tr1 cells at various disease stages
• IL-23 immune activity is more significant in early stages of axSpA
• Differences in Tr1 cell regulation appear across disease progression