Hamartomas of the head and neck region, though uncommon, represent a diverse group of benign developmental anomalies, with their clinical incidence estimated to range from 0.3% to 10% of all benign soft tissue tumors occurring in these sites. Folliculo sebaceous cystic hamartoma (FSCH) is a rare, benign cutaneous hamartoma with an estimated incidence of <1% among excised skin lesions. It typically presents as a slow-growing, skin-colored to yellowish papule or nodule, Folliculo-sebaceous cystic hamartoma is generally occurs in adults but can be seen in children and, rarely, congenitally. Histopathologically, Folliculo sebaceous cystic hamartoma is characterized by a cystically dilated follicular infundibulum connected to the epidermis, surrounded by multiple mature sebaceous lobules. Unlike sebaceous trichofolliculoma, Folliculo-sebaceous cystic hamartoma lacks secondary hair follicles and prominent hair shafts. Diagnosis is confirmed by histological examination, post surgical excision, with recurrence being rare.The non-specific clinical presentation of Folliculo-sebaceous cystic hamartoma results frequently as being underdiagnosed. A definitive diagnosis is achieved solely through histopathological examination.
Chinnathamb et al. (Sat,) studied this question.