Immunogenicity of HPV Vaccine in a High-Risk and Understudied Group: Female Sex Workers | Synapse
March 3, 2026
Immunogenicity of HPV Vaccine in a High-Risk and Understudied Group: Female Sex Workers
Key Points
This research aims to assess the immune response to the HPV vaccine among female sex workers.
Administered three doses of the 4vHPV vaccine to female sex workers
Measured the neutralizing antibodies (NAb) for HPV16 and HPV18
Evaluated immunogenicity of the vaccine in this specific population.
The vaccine produced a strong neutralizing antibody response to HPV16 and HPV18
Findings suggest a positive immunogenic response among female sex workers
Indicates the potential need for further effectiveness studies in this group.
Abstract
Three doses of 4vHPV elicited robust NAb to HPV16 and HPV18 among FSW. Further studies are needed to evaluate the effectiveness of HPV vaccination in FSW.