Comparison of Morphological Signs of Neurodegenerative Changes and Expression of Neuroprotective Factors in Adult and Aged Wistar Rats in AlCl3-Induced Neurodegeneration | Synapse
March 3, 2026
Comparison of Morphological Signs of Neurodegenerative Changes and Expression of Neuroprotective Factors in Adult and Aged Wistar Rats in AlCl3-Induced Neurodegeneration
Key Points
Neurodegenerative changes are more pronounced in aged Wistar rats compared to adults, indicating age-related vulnerability.
Expression of neuroprotective factors is significantly altered in response to aluminum chloride induction of neurodegeneration in both groups.
Evaluation involved analyzing morphological signs and expression levels of neuroprotective factors in Wistar rats exposed to neurodegenerative agents.
Findings suggest that aging may affect the mechanisms of neuroprotection and vulnerability in neurodegenerative conditions.