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Cancer-associated fibroblasts-derived exosomes in colorectal cancer progression: Mechanism and therapeutic opportunities | Synapse
March 3, 2026
Cancer-associated fibroblasts-derived exosomes in colorectal cancer progression: Mechanism and therapeutic opportunities
LY
Linling Yang
PA
Parastoo Akbarabadi
SB
Sadegh Babashah
Key Points
Cancer-associated fibroblasts' exosomes contribute to colorectal cancer progression by influencing the tumor microenvironment.
Increased levels of specific exosomal markers correlate with aggressive tumor characteristics in colorectal cancer.
Assessment of exosomal activity provides insights into potential therapeutic strategies targeting cancer-associated fibroblasts.
Highlights the need for further exploration of exosome-related therapies in colorectal cancer treatment.
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Yang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a93c6e9836116a20932
https://doi.org/https://doi.org/10.1016/j.bbcan.2026.189545
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