Single-cell proteomic landscape of the developing human brain

Key Points

• Distinct protein expression patterns were identified across various cell types in the developing brain, encompassing neurogenic phases.
• Notably, unique protein markers were linked to specific cell types, emphasizing a complex regulatory network within the brain.
• Utilizing single-cell proteomics techniques, multiple layers of cellular diversity were mapped, detailing individual contributions to overall brain function.
• This comprehensive analysis highlights the need for further exploration into protein interactions, given its potential implications for neurodevelopmental disorders.