Smoking and systemic Th17/Treg immune alterations in periodontitis: A cross-sectional study

Key Points

• Immune alterations were observed in Th17 and Treg cells in smokers with periodontitis, highlighting the impact of smoking on immune responses.
• The study identifies significant differences in immune profiles, particularly in cytokine production, related to smoking status.
• Assessment used cross-sectional analysis to evaluate immune changes in individuals with periodontitis and varying smoking histories.
• Understanding these immune alterations may inform future therapeutic strategies for periodontal disease, indicating a need for targeted interventions.