Risk factors and outcomes for steroid-refractory immune-related hepatotoxicity in locally advanced and metastatic cancer

Key Points

• Immune-related hepatotoxicity is significantly affected by specific risk factors, impacting patient outcomes.
• The analysis includes patients with both locally advanced and metastatic cancer presenting this condition.
• Assessment of treatment response reveals that certain risk factors worsen steroid-refractoriness in immune-related hepatotoxicity.
• Highlighting these risk factors may enable improved management strategies in affected cancer populations.