Genome-wide association and integrative analyses of relative handgrip strength identify polygenic determinants of gastrointestinal disorder susceptibility

Key Points

• Polygenic determinants reveal significant associations with gastrointestinal disorder susceptibility and handgrip strength.
• The study identifies novel genetic markers that correlate with strength measurements across various populations.
• Analysis integrates data from genome-wide association studies assessing handgrip strength to understand disorder links.
• Findings highlight the need for further research into genetic influences on gastrointestinal health and strength.