A multi-rotor near-infrared probe for high-sensitivity imaging of mitochondrial viscosity in epilepsy

Key Points

• Elevated mitochondrial viscosity is visualized in epileptic neurons and mouse hippocampus in vivo.
• Mitochondrial viscosity imaging was achieved using the near-infrared fluorescent probe Cy-TPE.
• The TICT-mediated multi-rotor design enhances sensitivity to viscosity changes, supporting detailed imaging capabilities.
• Further exploration of mitochondrial viscosity could uncover new insights into epilepsy mechanisms.