Non-Arteritic Ischaemic Optic Neuropathy Associated with Semaglutide Use. | Synapse
March 3, 2026
Non-Arteritic Ischaemic Optic Neuropathy Associated with Semaglutide Use.
Key Points
Non-arteritic ischaemic optic neuropathy (NAION) is linked with semaglutide use, which raises concerns.
The potential risk factor was identified in a case not previously reported in Ireland.
This observational report highlights possible implications for using GLP-1 receptor agonists.
More awareness is needed, as NAION cases associated with GLP-1RAs may be under-recognized.
Abstract
GLP-1RAs such as Semaglutide are being increasingly recognised as a potential risk factor for NAION. A case such as this has not yet been reported in Ireland.