Alterations in the DTI-ALPS index and choroid plexus volume as brain–immune interfacing indicators in neuropsychiatric lupus erythematosus with inflammatory phenotype

Key Points

• The DTI-ALPS index and choroid plexus volume are potential biomarkers for neuropsychiatric lupus erythematosus (NPSLE), indicating unique subtypes.
• Both indicators appear to reflect underlying mechanisms of central nervous system damage in this condition, thus expanding diagnostic tools.
• Assessment utilized neuroimaging techniques to measure these biomarkers in patients with inflammatory phenotype characteristics.
• These findings highlight the need for further investigation into brain-immune interfaces to improve understanding and treatment.