Total Testosterone Measured by Liquid Chromatograph‐Tandem Mass Spectrometry Refines Diagnosis of Biochemical Hyperandrogenism and Better Identifies Subgroup at Genuine Risk of Adverse Fertility Outcomes in Women With Polycystic Ovary Syndrome
Key Points
Biochemical hyperandrogenism is better diagnosed with total testosterone levels measured by liquid chromatography-tandem mass spectrometry,
Data analysis from both the NIH and Chinese Clinical Trial Registry emphasizes the importance of accurate testosterone measurement in identifying at-risk women.
This approach helps pinpoint individuals who may face adverse fertility outcomes due to polycystic ovary syndrome,
Improving diagnostic precision could lead to more effective management strategies for reproductive health in women suffering from PCOS.
Abstract
The NIH Clinical Trial Registry number: NCT01573858 and Chinese Clinical Trial. Registry number: ChiCTR-TRC-12002081.
Total Testosterone Measured by Liquid Chromatograph‐Tandem Mass Spectrometry Refines Diagnosis of Biochemical Hyperandrogenism and Better Identifies Subgroup at Genuine Risk of Adverse Fertility Outcomes in Women With Polycystic Ovary Syndrome | Synapse