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Tributyl phosphate disrupts hepatic lipid metabolism via cGAS-STING signal pathway mediated inflammation | Synapse
March 3, 2026
Tributyl phosphate disrupts hepatic lipid metabolism via cGAS-STING signal pathway mediated inflammation
LY
Liwei Yang
ZG
Zhili Ge
Jilin University
XD
Xuehan Ding
Jilin University
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Key Points
Hepatic lipid metabolism is disrupted by tributyl phosphate, leading to increased inflammation.
Key evidence shows elevated lipid levels linked to cGAS-STING pathways in liver cells.
The analysis employed investigates the relationship between tributyl phosphate and lipid dysregulation.
This work highlights potential environmental impacts on liver health through chemical exposure.
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Yang et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75bc2c6e9836116a23aef
https://doi.org/https://doi.org/10.1016/j.toxlet.2026.111847