Cluster 10 was found to contain three phages with exceptionally broad host ranges, highlighting its strong potential for therapeutic development. Additionally, the three conserved enzymes shared across multiple clusters, especially the endolysins, may serve as valuable tools for phage engineering due to their broad conservation. The cluster-specific phams offer biological insights and may also form the basis for developing cluster-specific primers or molecular diagnostics. Collectively, these findings deepen our understanding of Acinetobacter phage diversity and point toward new avenues for advancing phage-based therapies and diagnostics.
Pang et al. (Wed,) studied this question.