Transcriptomic insights into the immune dynamics of wild-type mice challenged with SARS-CoV-2 Beta variant

Key Points

• Immune dynamics are significantly altered in wild-type mice infected with SARS-CoV-2 Beta variant, demonstrating complex responses.
• The study identifies key transcriptomic changes, highlighting over 100 differentially regulated genes linked to viral infection.
• Transcriptomic analysis focuses on lung tissues, providing a detailed view of pathogen-induced immune responses.
• Insights into pathogenic events pave the way for further research on the efficacy of vaccine strategies and treatments.