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March 3, 2026
Signaling to make human ribosomes: Connections between the cytoplasm and the nucleolus
IL
Isabella Rachel Lawrence
Yale University
ES
Emily C. Sutton
Yale University
SB
Shivang Bhaskar
Yale University
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Key Points
Signaling pathways play a crucial role in ribosome production, linking the cytoplasm and nucleolus.
Understanding these connections can enhance our knowledge of protein synthesis in human cells.
The study investigates how alterations in signaling affect ribosomal biogenesis.
Findings may lead to insights into diseases related to ribosome dysfunction.
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Lawrence et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75ce2c6e9836116a261fc
https://doi.org/https://doi.org/10.1016/j.molcel.2026.01.007
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Signaling to make human ribosomes: Connections between the cytoplasm and the nucleolus | Synapse