March 3, 2026Open Access

Peripheral Immune Remodeling After Spinal Cord Injury

Key Points

Immune cell activation and exhaustion markers show significant changes, indicating immune vulnerability.
Key evidence includes modifications in immune profiles that could lead to therapeutic strategies.
Analysis highlights peripheral immune remodeling through targeted approaches aimed at NAD metabolism.
Findings suggest further exploration to establish effective therapies in managing immune responses post-injury.

Abstract

These findings reveal noteworthy changes in immune cell activation and exhaustion markers that may contribute to immune vulnerability after SCI, offering novel insights into potential therapeutic targets, such as NAD+ metabolism and immune checkpoint modulation.

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Discussion

Cite this study

Veeningen et al. (Wed,) studied this question.

synapsesocial.com/papers/69a75cf0c6e9836116a263bc — DOI: https://doi.org/10.1212/nxi.0000000000200544

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Authors

Naomi Veeningen

Hasselt University

Ana Laura Añé-Kourí

Hasselt University

A. Pues

Hasselt University

Journals

Neurology Neuroimmunology & Neuroinflammation

Actions

Institutions

Maastricht University

Hasselt University

Universitair Ziekenhuis Brussel

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Peripheral Immune Remodeling After Spinal Cord Injury

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Also consider