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Methotrexate intolerance in rheumatoid arthritis: Prevalence, risk factors and impact on treatment adherence | Synapse
March 3, 2026
Methotrexate intolerance in rheumatoid arthritis: Prevalence, risk factors and impact on treatment adherence
AE
Aya K. El-Hindawy
HR
Hala A. Raafat
MM
Marwa Magdy
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Key Points
Methotrexate intolerance significantly affects treatment adherence in patients with rheumatoid arthritis, leading to potential worsened outcomes.
The study identifies key risk factors including age and prior treatment experiences that correlate with intolerance.
Observational analysis assesses the prevalence of methotrexate intolerance and its implications for patient management.
Highlighting the need for tailored treatment plans may improve adherence and overall outcomes for affected individuals.
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El-Hindawy et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75d27c6e9836116a26b40
https://doi.org/https://doi.org/10.1016/j.ejr.2026.01.006