Does Hormone Replacement Therapy Influence Melasma Development? A Review of the Evidence and Management Guidelines

Key Points

• Melasma risk is increased in women receiving hormone replacement therapy, and more studies are needed.
• A strong emphasis should be placed on photoprotection measures for women at risk of developing melasma.
• Prospective studies aim to clarify the relationship between various hormone replacement therapy formulations and melasma.
• Counseling at-risk women is crucial for preventing the onset of melasma and enhancing treatment outcomes.